The company is launching a "Summer Essentials" package aimed at young, fun-seeking holidaymakers, with 67 advertising panels at Gatwick, Stansted, Luton, Edinburgh and Glasgow airports.
The panels have a potential reach of 10.6 million passengers a month, while a "Clubbers Special" package will also include corresponding ads at airports in Palma and Ibiza.
Richard Malton, marketing director at JCDecaux Airport, said the packages would suit clients in the fast-moving consumer goods sector, music brands, or new technology and mobile communications.
Malton said: "The campaign targets the traditionally hard to reach 18 to 34 (year-old) audience at a time when they are in the right mindset to spend and have time on their hands.
"It's an opportunity to influence last-minute purchase decisions for a brand-loyal audience in the retail-friendly environment of an airport."
Findings from Airport Ethnographic Research show that heart rate and ad receptiveness both increase when people are in airports, at both drop-off and check-in.