The former editor of The Sun newspapers is being charged by the Crown Prosecution Service (CPS) with the offence.
Brooks was arrested along with her husband Charlie Brooks on 13 March this year by Scotland Yard officers on suspicion of perverting the course of justice.
Brooks has been charged with three counts of conspiracy to pervert the course of justice and Charlie Brooks has been charged with two counts of conspiracy to pervent the course of justice.
The CPS said Brooks and her husband will appear before Westminster Magistrates Court on a date to be determined.
In a statement Rebekah and Charlie Brooks said: "We deplore this weak and unjust decision. After the further unprecedented posturing of the CPS we will respond later today after our return from the police station."
Along with Brooks and her husband, four other people have been charged by the CPS.
They are Brooks' former PA Cheryl Carter, News International’s head of security Mark Hanna, News International chauffeur Paul Edwards and Daryl Jorsling, who provided security to Brooks.
The charges are listed in full below:
CHARGE 1 – CONSPIRACY TO PERVERT THE COURSE OF JUSTICE
Rebekah Brooks between 6th July and 19th July 2011 conspired with Charles Brooks, Cheryl Carter, Mark Hanna, Paul Edwards, Daryl Jorsling and persons unknown to conceal material from officers of the Metropolitan Police Service
CHARGE 2 - CONSPIRACY TO PERVERT THE COURSE OF JUSTICE
Rebekah Brooks and Cheryl Carter between 6th July and 9th July 2011 conspired together permanently to remove seven boxes of material from the archive of News International.
CHARGE 3 – CONSPIRACY TO PERVERT THE COURSE OF JUSTICE
Rebekah Brooks, Charles Brooks, Mark Hanna, Paul Edwards and Daryl Jorsling conspired together and with persons unknown, between 15th July and 19th July 2011, to conceal documents, computers and other electronic equipment from officers of the Metropolitan Police Service.