The ad depicts five stages in the life of one man named Michael, who has been supported by Barnardo's through years of abuse and difficulty.
The campaign explains how the charity can help people from all walks of life.
The creative team behind the ad decided to use old-fashioned editing techniques to portray the changes in Michael's age rather than CGI technology.
Nick Gill, executive creative director at BBH said, "It's about people, it's about children, it's about a charity's fundamental belief that children with the toughest start in life can change, can be given a chance."
The film was shot by acclaimed director Ringan Ledwidge, who kick-started his career in 1999 by winning the Best Young Director accolade at Cannes.
Ledwidge shot the ad with hand-held cameras to create an intimate "home movie" effect.